The Potential Impact of a Gel-Based Point-of-Sex Intervention in Reducing Gonorrhea Incidence Among Gay and Bisexual Men: A Modeling Study
Michael W Traeger, Tom Tidhar, Martin Holt, Chris Williams, Edwina J Wright, Mark A Stoove, Nick Scott, Margaret E Hellard
SEXUALLY TRANSMITTED DISEASES | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020
BACKGROUND: Increases in sexually transmitted infections among gay and bisexual men (GBM) over the past decade have coincided with declines in condom use and rapid uptake of HIV preexposure prophylaxis (PrEP). We explored the impact of an antimicrobial gel-based point-of-sex intervention (gel-PSI) with a lower efficacy for reducing gonorrhea transmission risk than condoms on population-level gonorrhea incidence among GBM in Victoria, Australia. METHODS: A deterministic compartmental model of HIV and gonorrhea transmission was used to project annual gonorrhea incidence from 2020 to 2025. Individuals were classified as HIV-negative (PrEP or non-PrEP users) or HIV-positive, and further stratifi..View full abstract
Awarded by National Health and Medical Research Council
All authors declare no conflicts of interest. This work was supported by The Victorian Department of Health and Human Services through support for surveillance projects within the Burnet Institute. The National Health and Medical Research Council provide funding to M.E.H. as a Principal Research Fellow (1112297) and M.A.S. as a Career Development Fellow (1090445). N.S. is supported by funding through the Margaret and Jim Beaver fellowship.