Journal article
2020 international consensus on ANCA testing beyond systemic vasculitis
S Moiseev, JW Cohen Tervaert, Y Arimura, DP Bogdanos, E Csernok, J Damoiseaux, M Ferrante, LF Flores-Suárez, MJ Fritzler, P Invernizzi, D Jayne, JC Jennette, MA Little, SP McAdoo, P Novikov, CD Pusey, A Radice, AD Salama, JA Savige, M Segelmark Show all
Autoimmunity Reviews | ELSEVIER | Published : 2020
Abstract
This document follows up on a 2017 revised international consensus on anti-neutrophil cytoplasm antibodies (ANCA) testing in granulomatosis with polyangiitis and microscopic polyangiitis and focuses on the clinical and diagnostic value of ANCA detection in patients with connective tissue diseases, idiopathic interstitial pneumonia, autoimmune liver diseases, inflammatory bowel diseases, anti-glomerular basement membrane (GBM) disease, infections, malignancy, and during drug treatment. Current evidence suggests that in certain settings beyond systemic vasculitis, ANCA may have clinical, pathogenic and/or diagnostic relevance. Antigen-specific ANCA targeting proteinase-3 and myeloperoxidase sh..
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