Journal article

Predicting Nasal High-Flow Treatment Success in Newborn Infants with Respiratory Distress Cared for in Nontertiary Hospitals

Megan McKimmie-Doherty, Gaston RB Arnolda, Adam G Buckmaster, Louise S Owen, Kate A Hodgson, Ian MR Wright, Calum T Roberts, Peter G Davis, Brett J Manley

The Journal of Pediatrics | MOSBY-ELSEVIER | Published : 2020

Abstract

OBJECTIVE: To evaluate demographic and clinical variables as predictors of nasal high-flow treatment success in newborn infants with respiratory distress cared for in Australian nontertiary special care nurseries. STUDY DESIGN: A secondary analysis of the HUNTER trial, a multicenter, randomized controlled trial evaluating nasal high-flow as primary respiratory support for newborn infants with respiratory distress who were born ≥31 weeks of gestation and with birth weight ≥1200 g, and cared for in Australian nontertiary special care nurseries. Treatment success within 72 hours after randomization to nasal high-flow was determined using objective criteria. Univariable screening and multivariab..

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Grants

Awarded by Medical Research Future Fund (Australia) Next Generation Clinical Researchers Career Development Fellowship


Awarded by National Health and Medical Research Council (Australia)


Funding Acknowledgements

Supported by the Medical Research Future Fund (Australia) Next Generation Clinical Researchers Career Development Fellowship (1159225 [to B.M.]); National Health and Medical Research Council (Australia), Career Development Fellowship (1159444 [to L.O.]); National Health and Medical Research Council (Australia), Emerging Leadership Grant (1175634 [to C.R.]); National Health and Medical Research Council (Australia), Practitioner Fellowship (1157782 [to P.D.]). The authors declare no conflicts of interest.