Journal article
Parental occupational exposure pre- A nd post-conception and development of asthma in offspring
K Pape, C Svanes, CS Sejbæk, A Malinovschi, B Benediktsdottir, B Forsberg, C Janson, G Benke, G Tjalvin, JL Sánchez-Ramos, JP Zock, K Toren, L Bråbäck, M Holm, R Jõgi, RJ Bertelsen, T Gíslason, T Sigsgaard, X Liu, KS Hougaard Show all
International Journal of Epidemiology | OXFORD UNIV PRESS | Published : 2020
DOI: 10.1093/ije/dyaa085
Abstract
Background: While direct effects of occupational exposures on an individual's respiratory health are evident, a new paradigm is emerging on the possible effects of pre-conception occupational exposure on respiratory health in offspring. We aimed to study the association between parental occupational exposure starting before conception and asthma in their offspring (at 0-15 years of age). Methods: We studied 3985 offspring participating in the Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) generation study. Their mothers or fathers (n = 2931) previously participated in the European Community Respiratory Health Survey (ECRHS). Information was obtained from questionnaires..
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Awarded by Wellcome Trust
Funding Acknowledgements
This work was supported by funding from The Faculty of Health, Aarhus University, Denmark [Project No. 240008], The Wood Dust Foundation [Project No. 444508795], The Danish Lung Association, the Swedish Heart and Lung Foundation, the Swedish Association Against Asthma and Allergy, the Swedish Association against Heart and Lung Disease, the Swedish Council for Working Life and Social Research, The Bror Hjerpstedt Foundation, The Vardal Foundation for Health Care and Allergic Research, The Norwegian Research Council [project 135773/33], The Norwegian Asthma and Allergy Association, HelseVest Norway [Grant no. 911 631], NFR [Grant no. 214123, 230827/F20, 228174], The University of Iceland Research Fund, The Icelandic GP's Research Fund, The Estonian Science Foundation [Grant No. 4350], The Estonian Research Council [Grant no. PUT562], the Australian National Health Medical Research Council, Melbourne University, Sociedad Espanola de Neumologia y Cirugia Toracica, SEPAR Spain and Horizon2020 PHC1 [Grant no. 633212]. For more information, please see www.rhinessa.net.V.S.and C.S. are members of the COST BM1201 network. K.P. received a PhD scholarship from Aarhus University and the Danish Working Environment Research Fund, Denmark [Grant no. 17-2015-09/20150067134]. X.L. is supported by the Danish Council for Independent Research [Project No. DFF-5053-00156B].