Journal article

Parental occupational exposure pre- and post-conception and development of asthma in offspring

Kathrine Pape, Cecile Svanes, Camilla S Sejbaek, Andrei Malinovschi, Byndis Benediktsdottir, Bertil Forsberg, Christer Janson, Geza Benke, Gro Tjalvin, Jose Luis Sanchez-Ramos, Jan-Paul Zock, Kjell Toren, Lennart Braback, Mathias Holm, Rain Jogi, Randi J Bertelsen, Thorarin Gislason, Torben Sigsgaard, Xiaoqin Liu, Karin S Hougaard Show all

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY | OXFORD UNIV PRESS | Published : 2020

Abstract

BACKGROUND: While direct effects of occupational exposures on an individual's respiratory health are evident, a new paradigm is emerging on the possible effects of pre-conception occupational exposure on respiratory health in offspring. We aimed to study the association between parental occupational exposure starting before conception and asthma in their offspring (at 0-15 years of age). METHODS: We studied 3985 offspring participating in the Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) generation study. Their mothers or fathers (n = 2931) previously participated in the European Community Respiratory Health Survey (ECRHS). Information was obtained from questionnaires..

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Grants

Awarded by Faculty of Health, Aarhus University, Denmark


Awarded by Wood Dust Foundation


Awarded by Norwegian Research Council


Awarded by HelseVest Norway


Awarded by NFR


Awarded by Estonian Science Foundation


Awarded by Estonian Research Council


Awarded by Horizon2020 PHC1


Awarded by Danish Working Environment Research Fund, Denmark


Awarded by Danish Council for Independent Research


Funding Acknowledgements

This work was supported by funding from The Faculty of Health, Aarhus University, Denmark [Project No. 240008], The Wood Dust Foundation [Project No. 444508795], The Danish Lung Association, the Swedish Heart and Lung Foundation, the Swedish Association Against Asthma and Allergy, the Swedish Association against Heart and Lung Disease, the Swedish Council for Working Life and Social Research, The Bror Hjerpstedt Foundation, The Vardal Foundation for Health Care and Allergic Research, The Norwegian Research Council [project 135773/33], The Norwegian Asthma and Allergy Association, HelseVest Norway [Grant no. 911 631], NFR [Grant no. 214123, 230827/F20, 228174], The University of Iceland Research Fund, The Icelandic GP's Research Fund, The Estonian Science Foundation [Grant No. 4350], The Estonian Research Council [Grant no. PUT562], the Australian National Health Medical Research Council, Melbourne University, Sociedad Espanola de Neumologia y Cirugia Toracica, SEPAR Spain and Horizon2020 PHC1 [Grant no. 633212]. For more information, please see www.rhinessa.net.V.S.and C.S. are members of the COST BM1201 network. K.P. received a PhD scholarship from Aarhus University and the Danish Working Environment Research Fund, Denmark [Grant no. 17-2015-09/20150067134]. X.L. is supported by the Danish Council for Independent Research [Project No. DFF-5053-00156B].