Rapid Gel Card Agglutination Assays for Serological Analysis Following SARS-CoV-2 Infection in Humans
Diana Alves, Rodrigo Curvello, Edward Henderson, Vidhishri Kesarwani, Julia A Walker, Samuel C Leguizamon, Heather McLiesh, Vikram Singh Raghuwanshi, Hajar Samadian, Erica M Wood, Zoe K McQuilten, Maryza Graham, Megan Wieringa, Tony M Korman, Timothy F Scott, Mark M Banaszak Holl, Gil Garnier, Simon R Corrie
ACS Sensors | AMER CHEMICAL SOC | Published : 2020
High-throughput and rapid serology assays to detect the antibody response specific to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) in human blood samples are urgently required to improve our understanding of the effects of COVID-19 across the world. Short-term applications include rapid case identification and contact tracing to limit viral spread, while population screening to determine the extent of viral infection across communities is a longer-term need. Assays developed to address these needs should match the ASSURED criteria. We have identified agglutination tests based on the commonly employed blood typing methods as a viable option. These blood typing tests are employ..View full abstract
The authors acknowledge funding support from the Chemical Engineering Department and the Centre to Impact Anti-Microbial Resistance at Monash University to undertake this project. They also acknowledge the Australian Red Cross Lifeblood for providing clinical samples.