Journal article
Associations between grass pollen exposures in utero and in early life with food allergy in 12-month-old infants
NH Susanto, AJ Lowe, A Salim, JJ Koplin, MLK Tang, NHA Suaini, AL Ponsonby, KJ Allen, SC Dharmage, B Erbas
International Journal of Environmental Health Research | TAYLOR & FRANCIS LTD | Published : 2020
Abstract
Birth during pollen seasons may influence food allergy risk but no study has assessed pollen exposure. Using the HealthNuts population-based cohort of 5276 infants, we assessed grass pollen exposures, in utero and up to the first 6 months of life, on hen’s egg, sesame and peanut allergy outcomes at 12 months. Cumulative pollen exposure in the first 7 days of life increased risk of peanut sensitization aMOR (adjusted multinomial odds ratio) = 1.21 (95% CI: 1.01–1.44). Exposure between first 4–6 months of life increased risk of hen’s egg aMOR = 1.02 (95% CI: 1.004–1.04) and sensitization to all foods aMOR = 1.02 (95% CI: 1.003–1.04). Grass pollen exposure was associated with food challenge dia..
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Funding Acknowledgements
This work was supported by funding from the National Health & Medical Research Council (NHMRC) of Australia; Ilhan Food Allergy Foundation; AnaphylaxiStop; the Charles and Sylvia Viertel Medical Research Foundation; the Victorian Government's Operational Infrastructure Support Program; and the NHMRC Centre for Food and Allergy Research. K.J.A., A.J.L., J.J.K., and S.C.D. hold NHMRC awards.