Comparison of the Hemodynamic and Temperature Effects of a 500-mL Bolus of 4% Albumin at Room Versus Body Temperature in Cardiac Surgery Patients

Abstract

Objective: To compare the hemodynamic effect of room temperature (cold) 4% albumin fluid bolus therapy (FBT) with body temperature (warm) albumin FBT. Design: Prospective, before-after trial. Setting: A tertiary intensive care unit (ICU). Participants: Sixty ventilated, post-cardiac surgery patients prescribed with 4% albumin FBT. Intervention: Cold or warm 4% albumin 500 ml FBT. Measurements and Main Results: We recorded hemodynamic parameters before and for 30 minutes after FBT. Cardiac index (CI) and mean arterial pressure (MAP) responses were defined by a CI increase >15% and a MAP increase >10%, respectively. Immediately after FBT, median [interquartile range] core temperature changed b..