Occupational and environmental risk factors for idiopathic pulmonary fibrosis in Australia: case-control study
Michael J Abramson, Tsitsi Murambadoro, Sheikh M Alif, Geza P Benke, Shyamali C Dharmage, Ian Glaspole, Peter Hopkins, Ryan F Hoy, Sonja Klebe, Yuben Moodley, Shuli Rawson, Paul N Reynolds, Rory Wolfe, Tamera J Corte, E Haydn Walters
Thorax | BMJ PUBLISHING GROUP | Published : 2020
INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a lung disease of unknown cause characterised by progressive scarring, with limited effective treatment and a median survival of only 2-3 years. Our aim was to identify potential occupational and environmental exposures associated with IPF in Australia. METHODS: Cases were recruited by the Australian IPF registry. Population-based controls were recruited by random digit dialling, frequency matched on age, sex and state. Participants completed a questionnaire on demographics, smoking, family history, environmental and occupational exposures. Occupational exposure assessment was undertaken with the Finnish Job Exposure Matrix and Australian ..View full abstract
Awarded by National Health and Medical Research Council of Australia
This project was funded by the National Health and Medical Research Council of Australia (Project Grant #1106601). Shyamali Dharmage, Paul Reynolds and E. Haydn Walters are also supported by NHMRC. Tamera Corte, Ian Glaspole, Yuben Moodley and E. Haydn Walters hold a Centre of Research Excellence Grant in Pulmonary Fibrosis from NHMRC. Lung Foundation Australia established the Australian IPF Registry with the generous support of a philanthropic family and industry sponsors including Boehringer Ingelheim, Roche Products, Galapagos and Bristol-Myers Squibb Australia.