Journal article

Occupational and environmental risk factors for idiopathic pulmonary fibrosis in Australia: case-control study

Michael J Abramson, Tsitsi Murambadoro, Sheikh M Alif, Geza P Benke, Shyamali C Dharmage, Ian Glaspole, Peter Hopkins, Ryan F Hoy, Sonja Klebe, Yuben Moodley, Shuli Rawson, Paul N Reynolds, Rory Wolfe, Tamera J Corte, E Haydn Walters

Thorax | BMJ PUBLISHING GROUP | Published : 2020

Abstract

INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a lung disease of unknown cause characterised by progressive scarring, with limited effective treatment and a median survival of only 2-3 years. Our aim was to identify potential occupational and environmental exposures associated with IPF in Australia. METHODS: Cases were recruited by the Australian IPF registry. Population-based controls were recruited by random digit dialling, frequency matched on age, sex and state. Participants completed a questionnaire on demographics, smoking, family history, environmental and occupational exposures. Occupational exposure assessment was undertaken with the Finnish Job Exposure Matrix and Australian ..

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Grants

Awarded by National Health and Medical Research Council of Australia


Funding Acknowledgements

This project was funded by the National Health and Medical Research Council of Australia (Project Grant #1106601). Shyamali Dharmage, Paul Reynolds and E. Haydn Walters are also supported by NHMRC. Tamera Corte, Ian Glaspole, Yuben Moodley and E. Haydn Walters hold a Centre of Research Excellence Grant in Pulmonary Fibrosis from NHMRC. Lung Foundation Australia established the Australian IPF Registry with the generous support of a philanthropic family and industry sponsors including Boehringer Ingelheim, Roche Products, Galapagos and Bristol-Myers Squibb Australia.