Journal article

The impact of coronary heart disease prevention on work productivity: a 10-year analysis

Feby Savira, Bing H Wang, Andrew R Kompa, Zanfina Ademi, Alice J Owen, Danny Liew, Ella Zomer

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY | OXFORD UNIV PRESS | Published : 2021

Abstract

AIM: To assess the cost-effectiveness of dapagliflozin in addition to standard care versus standard care alone in patients with chronic heart failure and reduced ejection fraction. METHODS: A Markov model was constructed based on the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial to assess the clinical outcomes and costs of 1000 hypothetical subjects with established heart failure and reduced ejection fraction. The model consisted of three health states: 'alive and event-free', 'alive after non-fatal hospitalisation for heart failure' and 'dead'. Costs and utilities were estimated from published sources. The main outcome was the incremental cost-effectiveness ratio p..

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