Mortality in patients with psychogenic nonepileptic seizures
Russell Nightscales, Lara McCartney, Clarissa Auvrez, Gerard Tao, Sarah Barnard, Charles B Malpas, Piero Perucca, Anne McIntosh, Zhibin Chen, Shobi Sivathamboo, Sophia Ignatiadis, Simon Jones, Sophia Adams, Mark J Cook, Patrick Kwan, Dennis Velakoulis, Wendyl D'Souza, Samuel F Berkovic, Terence J O'Brien
Neurology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020
OBJECTIVE: To investigate the hypothesis that patients diagnosed with psychogenic nonepileptic seizures (PNES) on video-EEG monitoring (VEM) have increased mortality by comparison to the general population. METHODS: This retrospective cohort study included patients evaluated in VEM units of 3 tertiary hospitals in Melbourne, Australia, between January 1, 1995, and December 31, 2015. Diagnosis was based on consensus opinion of experienced epileptologists and neuropsychiatrists at each hospital. Mortality was determined in patients diagnosed with PNES, epilepsy, or both conditions by linkage to the Australian National Death Index. Lifetime history of psychiatric disorders in PNES was determine..View full abstract
Awarded by National Health and Medical Research Council
Supported by the National Health and Medical Research Council (APP1091593) and the RMH Neuroscience Foundation.