Journal article

Birth rates among male cancer survivors and mortality rates among their offspring: a population-based study from Sweden

Siau-Wei Tang, Jenny Liu, Lester Juay, Kamila Czene, Hui Miao, Agus Salim, Helena M Verkooijen, Mikael Hartman

BMC Cancer | BIOMED CENTRAL LTD | Published : 2016

Abstract

With improvements in treatment of cancer, more men of fertile age are survivors of cancer. This study evaluates trends in birth rates among male cancer survivors and mortality rates of their offspring.From the Swedish Multi-generation Register and Cancer Register, we identified 84,752 men ≤70 years with a history of cancer, for which we calculated relative birth rates as compared to the background population(Standardized Birth Ratios, SBRs). We also identified 126,696 offspring of men who had cancer, and compared their risks of death to the background population(Standardized Mortality Ratio, SMRs). Independent factors associated with reduced birth rates and mortality rates were estimated wit..

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Grants

Awarded by Swedish Initiative for research on Microdata in the Social and Medical Sciences (SIMSAM)


Awarded by National Medical Research Council, Singapore


Awarded by National University of Singapore Start-up Fund DPRT


Funding Acknowledgements

We would like to acknowledge the Swedish Research Council, Swedish Initiative for research on Microdata in the Social and Medical Sciences (SIMSAM), grant number 80748301; National Medical Research Council, Singapore (NMRC/1180/2008) and National University of Singapore Start-up Fund DPRT(Grant Number R-186-000-108-133).