Journal article

Mortality among offspring of women diagnosed with cancer: A population-based cohort study

Helena M Verkooijen, Joella X Ang, Jenny Liu, Kamila Czene, Agus Salim, Mikael Hartman

International Journal of Cancer | WILEY | Published : 2013

Abstract

One in five cancers in women is diagnosed prior to and during a woman's fertile years. Our study evaluates mortality risks in offspring of mothers with history of cancer. From the Swedish Multi-generation Register and the Cancer Register, we identified all 174,893 children whose mother had been diagnosed with cancer between 1958 and 2001. We categorized offspring into those born before (>1 year before), around (within 1 year before and after diagnosis) and after (>1 year after) their mother's cancer diagnosis and compared their risks of death (standardized mortality ratios, SMRs) and causes of death to the background population. Overall, offspring of mothers diagnosed with cancer had no incr..

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Grants

Awarded by Swedish Research Council (SIMSAM)


Awarded by National Medical Research Council, Singapore


Awarded by National University of Singapore Start-up Fund DPRT


Funding Acknowledgements

Grant sponsor: The Swedish Research Council (SIMSAM); Grant number: 80748301; Grant sponsor: National Medical Research Council, Singapore; Grant number: NMRC/1180/2008; Grant sponsor: National University of Singapore Start-up Fund DPRT; Grant number: R-186-000-108-133