Birth rates among female cancer survivors: A population-based cohort study in Sweden

Abstract

BACKGROUND: More women of fertile age are long-term survivors of cancer. However, population-based data on birth rates of female cancer survivors are rare. METHODS: A total of 42,691 women ≤ 45 years with a history of cancer were identified from the Swedish Multi-Generation Register and the Swedish Cancer Register, for whom relative birth rates were calculated as compared to the background population, ie, standardized birth ratios (SBRs). Independent factors associated with reduced birth rates among cancer survivors were estimated using Poisson modeling. RESULTS: Compared to the background population, cancer survivors were 27% less likely to give birth (SBR = 0.73, 95% confidence interval [C..