Journal article

Community-Based Adverse Food Reactions and Anaphylaxis in Children with IgE-Mediated Food Allergy at Age 6 Years: A Population-Based Study

Yichao Wang, Rachel L Peters, Kirsten P Perrett, Vicki L McWilliam, Mimi LK Tang, Adrian J Lowe, Anne-Louise Ponsonby, Shyamali C Dharmage, Katrina J Allen, Jennifer J Koplin



BACKGROUND: Few studies have investigated adverse food reactions among food-allergic children in a population-based sample, which is critical for the development of evidence-based management strategies. OBJECTIVE: We aimed to evaluate the frequency, characteristics, and risk factors for adverse food reactions, including anaphylaxis, among food-allergic 6-year-old-children using the population-based HealthNuts study. METHODS: The HealthNuts study of 5276 infants (1-year-old) followed them up at age 6 years (84.4% participated). A total of 260 children with IgE-mediated food allergy who completed a questionnaire detailing recent adverse food reactions were included in this analysis. RESULTS: A..

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Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

Y.W. received the Melbourne International Research Scholarship and Melbourne International Fee Remission Scholarship from The University of Melbourne and Top-up Scholarship from Murdoch Children's Research Institute. This study was supported by the National Health and Medical Research Council of Australia (grant no. GNT 1006215), the Australian Food Allergy Foundation, and the Victorian Government's Operational Infrastructure Support Program. R.L.P., A.J.L, S.C.D., K.J.A, and J.J.K. hold or held NHMRC fellowships. K.P.P. holds a Melbourne Children's Clinician Scientist Fellowship.