Journal article

Cost-effectiveness of inhaled oxytocin for prevention of postpartum haemorrhage: a modelling study applied to two high burden settings

Natalie Carvalho, Mohammad Enamul Hoque, Victoria L Oliver, Abbey Byrne, Michelle Kermode, Pete Lambert, Michelle P McIntosh, Alison Morgan

BMC Medicine | BMC | Published : 2020

Abstract

BACKGROUND: Access to oxytocin for prevention of postpartum haemorrhage (PPH) in resource-poor settings is limited by the requirement for a consistent cold chain and for a skilled attendant to administer the injection. To overcome these barriers, heat-stable, non-injectable formulations of oxytocin are under development, including oxytocin for inhalation. This study modelled the cost-effectiveness of an inhaled oxytocin product (IHO) in Bangladesh and Ethiopia. METHODS: A decision analytic model was developed to assess the cost-effectiveness of IHO for the prevention of PPH compared to the standard of care in Bangladesh and Ethiopia. In Bangladesh, introduction of IHO was modelled in all pub..

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Grants

Awarded by Korea International Cooperation Agency


Funding Acknowledgements

This work was made possible through the generous support of the Saving Lives at Birth partners: the United States Agency for International Development, the Government of Norway, the Bill & Melinda Gates Foundation, Grand Challenges Canada, the UK Government and the Korea International Cooperation Agency (Grant #: AID-OAA-F-17-00012). The funders had no role in the design, conduct, analysis or writing up of the study. All authors had full access to the model and input data and jointly took the decision to submit for publication.