Journal article

Reduced live birth rates in frozen versus fresh single cleavage embryo transfer cycles: A cross -sectional study

Wan Tinn Teh, Alex Polyakov, Claire Garrett, David Edgar, John Mcbain, Peter Adrian Walton Rogers

INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE | SHAHID SADOUGHI UNIV MEDICAL SCIENCES | Published : 2020

Abstract

Background: Studies have suggested that embryo-endometrial developmental asynchrony caused by slow-growing embryos can be corrected by freezing the embryo and transferring it back in a subsequent cycle. Therefore, we hypothesized that live birth rates (LBR) would be higher in frozen embryo transfer (FET) compared with fresh embryo transfers. Objective: To compare LBR between fresh and FET cycles. Materials and Methods: A cross-sectional analysis of 10,744 single autologous embryo transfer cycles that used a single cleavage stage embryo was performed. Multivariate analysis was performed to compare LBR between FET and fresh cycles, after correcting for various confounding factors. Sub-analysis..

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