School-age outcomes following intraventricular haemorrhage in infants born extremely preterm

Abstract

Objective To determine the associations of different grades of intraventricular haemorrhage (IVH), particularly grades 1 and 2, with neurodevelopmental outcomes at 8 years of age in children born extremely preterm. Design Population-based cohort study. Setting State of Victoria, Australia. Patients Survivors born at <28 weeks' gestational age (n=546) and matched term-born controls (n=679) from three distinct eras, namely, those born in 1991-1992, 1997 and 2005. Exposure Worst grade of IVH detected on serial neonatal cranial ultrasound. Outcome measures Intellectual ability, executive function, academic skills, cerebral palsy and motor function at 8 years. Results There was a trend for increa..