Journal article

Evaluation of an artificial intelligence clinical trial matching system in Australian lung cancer patients

Marliese Alexander, Benjamin Solomon, David L Ball, Mimi Sheerin, Irene Dankwa-Mullan, Anita M Preininger, Gretchen Purcell Jackson, Dishan M Herath

JAMIA Open | OXFORD UNIV PRESS | Published : 2020

Abstract

Objective: The objective of this technical study was to evaluate the performance of an artificial intelligence (AI)-based system for clinical trials matching for a cohort of lung cancer patients in an Australian cancer hospital. Methods: A lung cancer cohort was derived from clinical data from patients attending an Australian cancer hospital. Ten phases I-III clinical trials registered on clinicaltrials.gov and open to lung cancer patients at this institution were utilized for assessments. The trial matching system performance was compared to a gold standard established by clinician consensus for trial eligibility. Results: The study included 102 lung cancer patients. The trial matching syst..

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