Journal article

A simplified (modified) Duke Activity Status Index (M-DASI) to characterise functional capacity: a secondary analysis of the Measurement of Exercise Tolerance before Surgery (METS) study

Bernhard Riedel, Michael H-G Li, CH Angus Lee, Hilmy Ismail, Brian H Cuthbertson, Duminda N Wijeysundera, Kwok M Ho



BACKGROUND: Accurate assessment of functional capacity, a predictor of postoperative morbidity and mortality, is essential to improving surgical planning and outcomes. We assessed if all 12 items of the Duke Activity Status Index (DASI) were equally important in reflecting exercise capacity. METHODS: In this secondary cross-sectional analysis of the international, multicentre Measurement of Exercise Tolerance before Surgery (METS) study, we assessed cardiopulmonary exercise testing and DASI data from 1455 participants. Multivariable regression analyses were used to revise the DASI model in predicting an anaerobic threshold (AT) >11 ml kg-1 min-1 and peak oxygen consumption (VO2 peak) >16 ml ..

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Funding Acknowledgements

KMH is funded by WA Health and Raine Medical Research Foundation through the Raine Clinical Research Fellowship. DW is supported in part by a New Investigator Award from the Canadian Institutes of Health Research, an Excellence in Research Award from the Department of Anesthesia at the University of Toronto, and the Endowed Chair in Translational Anesthesiology Research at St. Michael's Hospital and University of Toronto. The funding agencies have no influence on the choice of the subject matter, design of the study, data analyses, the decision to publish the results and the final content of the manuscript. The other authors have not received any funding. The METS study was funded by the Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; Ontario Ministry of Health and LongTerm Care; Ontario Ministry of Research, Innovation and Science; UK National Institute of Academic Anaesthesia; UK Clinical Research Collaboration; Australian and New Zealand College of Anaesthetists; Monash University.