Journal article

Current perspectives on the safe electrical stimulation of peripheral nerves with platinum electrodes

Alexander R Harris

Bioelectronics in Medicine | Future Medicine Ltd | Published : 2020


This review details some peripheral nervous system (PNS) targets and electrode designs used for electrical stimulation. It investigates limitations in current knowledge of safe electrical stimulation and possible future electrode developments. Current PNS targets are large, leading to poor resolution and off-target side-effects. Most clinical devices are platinum or platinum/iridium embedded in an insulation material. Their safety is usually guided by the Shannon plot, which is not valid for the PNS. New electrode designs are needed to target smaller nerve fibers, enabling higher resolution electrical therapies with fewer off-target side-effects. Damage can occur through biological and elect..

View full abstract

Citation metrics