Journal article

Statin intolerance: an updated, narrative review mainly focusing on muscle adverse effects

Jian-Jun Li, Hui-Hui Liu, Na-Qiong Wu, Khung Keong Yeo, Kathryn Tan, Junya Ako, Rungroj Krittayaphong, Ru San Tan, Philip E Aylward, Sang Hong Baek, Jamshed Dalal, Alan Yean Yip Fong, Yi-Heng Li, Richard C O'Brien, Tien Siang Eric Lim, Si Ya Natalie Koh, Daniel J Scherer, Hayato Tada, Vernon Kang, Julie Butters Show all

Expert Opinion on Drug Metabolism & Toxicology | TAYLOR & FRANCIS LTD | Published : 2020

Abstract

INTRODUCTION: Statins have been established as the standard of care for dyslipidemia and preventing cardiovascular diseases while posing few safety concerns. However, misconceptions about statin intolerance lead to their underuse, indicating a need to improve the understanding of the safety of this treatment. AREAS COVERED: We searched PubMed and reviewed literatures related to statin intolerance published between February 2015 and February 2020. Important large-scale or landmark studies published before 2015 were also cited as key evidence. EXPERT OPINION: Optimal lowering of low-density lipoprotein cholesterol with statins substantially reduces the risk of cardiovascular events. Muscle adv..

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University of Melbourne Researchers