Journal article
Statin intolerance: an updated, narrative review mainly focusing on muscle adverse effects
JJ Li, HH Liu, NQ Wu, KK Yeo, K Tan, J Ako, R Krittayaphong, RS Tan, PE Aylward, SH Baek, J Dalal, AYY Fong, YH Li, RC O’Brien, TSE Lim, SYN Koh, DJ Scherer, H Tada, V Kang, J Butters Show all
Expert Opinion on Drug Metabolism and Toxicology | Published : 2020
Abstract
Introduction: Statins have been established as the standard of care for dyslipidemia and preventing cardiovascular diseases while posing few safety concerns. However, misconceptions about statin intolerance lead to their underuse, indicating a need to improve the understanding of the safety of this treatment. Areas covered: We searched PubMed and reviewed literatures related to statin intolerance published between February 2015 and February 2020. Important large-scale or landmark studies published before 2015 were also cited as key evidence. Expert opinion: Optimal lowering of low-density lipoprotein cholesterol with statins substantially reduces the risk of cardiovascular events. Muscle adv..
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