Journal article

Impact of the 2017 American Heart Association and American College of Cardiology hypertension guideline in aged individuals

Enayet Karim Chowdhury, Michael E Ernst, Mark Nelson, Karen Margolis, Lawrie J Beilin, Collin Johnston, Robyn Woods, Anne Murray, Rory Wolfe, Elsdon Storey, Raj C Shah, Jessica Lockery, Andrew Tonkin, Anne Newman, Walter Abhayaratna, Nigel Stocks, Sharyn Fitzgerald, Suzanne Orchard, Ruth Trevaks, Geoffrey Donnan Show all

Journal of Hypertension | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020

Abstract

OBJECTIVES: The AHA/ACC-2017 hypertension guideline recommends an age-independent target blood pressure (BP) of less than 130/80 mmHg. In an elderly cohort without established cardiovascular disease (CVD) at baseline, we determined the impact of this guideline on the prevalence of hypertension and associated CVD risk. METHODS: Nineteen thousand, one hundred and fourteen participants aged at least 65 years from the ASPirin in Reducing Events in the Elderly (ASPREE) study were grouped by baseline BP: 'pre-2017 hypertensive' (BP ≥140/90 mmHg and/or on antihypertensive drugs); 'reclassified hypertensive' (normotensive by pre-2017 guidelines; hypertensive by AHA/ACC-2017 guideline), and 'normoten..

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Grants

Awarded by National Cancer Institute at the National Institutes of Health


Awarded by National Health and Medical Research Council of Australia


Funding Acknowledgements

The work was supported by the National Institute on Aging and the National Cancer Institute at the National Institutes of Health (grant number U01AG029824); the National Health and Medical Research Council of Australia (grant numbers 334047, 1127060); Monash University (Australia); and the Victorian Cancer Agency (Australia).