Journal article

Clinical characteristics and prognosis of anal squamous cell carcinoma: a retrospective audit of 144 patients from 11 cancer hospitals in southern China

Yong Lu, Xiaohao Wang, Peiyang Li, Tao Zhang, Jiaming Zhou, Yufeng Ren, Yi Ding, Haihua Peng, Qichun Wei, Kaiyun You, Jason J Ong, Christopher K Fairley, Andrew E Grulich, Meijin Huang, Yuanhong Gao, Huachun Zou

BMC CANCER | BMC | Published : 2020

Abstract

BACKGROUND: The incidence of anal squamous cell carcinoma (SCC) has been steadily growing globally in the past decade. Clinical data on anal SCC from China are rare. We conducted this study to describe the clinical and epidemiological characteristics of anal SCC in China and explore prognostic factors of outcomes among patients with anal SCC. METHODS: We audited demographic characteristics, relevant symptoms, risk factors, treatment modalities and outcomes for patients diagnosed with anal SCC at 11 medical institutions in China between January 2007 and July 2018. RESULTS: A total of 144 patients (109 females) were diagnosed with SCC during this period. Median age at initial diagnosis was 52...

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University of Melbourne Researchers

Grants

Awarded by Fund of National Natural Science Foundation of China


Awarded by Australian National Health and Medical Research Council


Awarded by Sanming Project of Medicine in Shenzhen, China


Awarded by Guangdong Natural Science Funds for Distinguished Young Scholar, China


Awarded by Guangdong Program for Support of Top-notch Young Professionals, China


Funding Acknowledgements

This work was supported by The Fund of National Natural Science Foundation of China [7191101234, 81172152, 81872470, 81572952 and 81672987]; Australian National Health and Medical Research Council Early Career Fellowship [APP1092621]; Sanming Project of Medicine in Shenzhen, China [SZSM201811071]; Guangdong Natural Science Funds for Distinguished Young Scholar, China [2015A030306015]; Guangdong Program for Support of Top-notch Young Professionals, China [2015TQ01R279]. The funding bodies played no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.