Journal article

In vitro Antioxidant, PTP-1B Inhibitory Effects and in vivo Hypoglycemic Potential of Selected Medicinal Plants

A Arya, CY Looi, WF Wong, MI Noordin, S Nyamathulla, MR Mustafa, M Ali Mohd

INTERNATIONAL JOURNAL OF PHARMACOLOGY | ASIAN NETWORK SCIENTIFIC INFORMATION-ANSINET | Published : 2013

Abstract

The therapeutic potential of plants varies according to their parts. The present study was aimed to ascertain the antioxidant and antidiabetic potential of crude fractions obtained from different parts of 6 medicinal plants, Centratherum anthelminticum, Cissus quadrangularis, Terminalia bellerica, Terminalia chebula, Terminalia arjuna and Woodfordia fruticosa. Total phenolic (TPC), total flavonoid (TFC) and total tannin content (TTC) were determined. In vitro antioxidant abilities were showed by 1, 1-diphenyl-2-picrylhydrazyl (DPPH), Oxygen Radical Absorbance Capacity (ORAC) and Ferric Reducing/antioxidant Power (FRAP) assays. Furthermore, anti-diabetic potential was determined using in vitr..

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University of Melbourne Researchers

Grants

Awarded by University of Malaya research


Awarded by BKP


Awarded by UMRG


Funding Acknowledgements

The study was funded by University of Malaya research grants UMRG (RG044111BIO), BKP (BK011-2012) and UMRG (RG041-10BIO). The authors sincerely thank Amritum Bio-Botanica Herbs Research Laboratory Pvt. Ltd. India for supplying the plant material.