Journal article

Food additive "lauric acid" possess non-toxic profile on biochemical, haematological and histopathological studies in female Sprague Dawley (SD) rats

Hidayat Ullah Khan, Khurram Aamir, Sreenivas Patro Sisinthy, Narendra Babu Shivanagere Nagojappa, Aditya Arya

PeerJ | PEERJ INC | Published : 2020

Abstract

Background Lauric acid (LA), a common constituent of coconut oil, is used as food additives and supplements in various formulations. Despite various potential pharmacological properties, no scientific evidence on its dose-related toxicity and safety is available till date. Objective The current study was conducted to evaluate acute oral toxicity of LA on normal rats. Methods The study was conducted in accordance with the Organization for Economic Co-operation and Development guidelines (OECD 423) with slight modifications. LA was administered orally to female Sprague..

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University of Melbourne Researchers

Grants

Awarded by Taylors University Flagship Research Grant under the umbrella of Ageing and Quality of Life


Funding Acknowledgements

The current study was funded by the Taylors University Flagship Research Grant (TUFR/2017/002/01) under the umbrella of Ageing and Quality of Life. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.