Journal article

Programmable Permeability of Metal–Phenolic Network Microcapsules

Jingqu Chen, Shuaijun Pan, Jiajing Zhou, Qi-Zhi Zhong, Yijiao Qu, Joseph J Richardson, Frank Caruso

Chemistry of Materials | American Chemical Society (ACS) | Published : 2020

Abstract

Developing materials with programmable permeability for cargo encapsulation and release is challenging but important in a number of fields including drug delivery and sensing. Metal–phenolic networks (MPNs) are an emerging class of hybrid coordination materials with pH-responsiveness and modularity that can be engineered into functional thin films for diverse applications. Herein, we engineer MPN-based microcapsules with a dynamic gating mechanism by adjusting the intermolecular interactions in the capsules. Altering the choice of building blocks and precursor ratio provides an intrinsic and modular means of tailoring capsule size and permeability. Alternatively, regulating the pH of the env..

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Grants

Awarded by Australian Research Council


Awarded by National Health and Medical Research Council


Funding Acknowledgements

This research was conducted and funded by the Australian Research Council Centre of Excellence in Convergent BioNano Science and Technology (Project No. CE140100036). F.C. acknowledges the award of a National Health and Medical Research Council Senior Principal Research Fellowship (GNT1135806). This work was performed in part at the Materials Characterisation and Fabrication Platform (MCFP) at The University of Melbourne and the Victorian Node of the Australian National Fabrication Facility (ANFF). Small-angle X-ray scattering experiments were conducted at the Australian Synchrotron (ANSTO Facilities). We thank Yiyuan Han and Zhixing Lin for helpful discussions.