Journal article

Sleep in autism: A biomolecular approach to aetiology and treatment

P Ballester, AL Richdale, EK Baker, AM Peiro

SLEEP MEDICINE REVIEWS | W B SAUNDERS CO LTD | Published : 2020

Abstract

People with autism spectrum disorder (ASD) commonly experience other comorbidities. Studies indicate that between 50% and 83% of individuals with ASD have sleep problems or disorders. The most commonly reported sleep problems are: (a) insomnia symptoms including the inability to get to sleep or stay asleep; and (b) circadian rhythm sleep-wake disorders, defined as a misalignment between the timing of endogenous circadian rhythms and the external environment. The circadian system provides timing information for the sleep-wake cycle that is regulated by the interaction of an endogenous processes (circadian - Process C, and homeostatic - Process S) and synchronizing agents (neurohormones and ne..

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