Journal article

A Monte Carlo model of synchrotron radiotherapy shows good agreement with experimental dosimetry measurements: Data from the imaging and medical beamline at the Australian Synchrotron

LRJ Day, P Pellicioli, F Gagliardi, M Barnes, LML Smyth, D Butler, J Livingstone, AW Stevenson, J Lye, CM Poole, D Hausermann, PAW Rogers, JC Crosbie

Physica Medica | ELSEVIER SCI LTD | Published : 2020

Abstract

Experimental measurement of Synchrotron Radiotherapy (SyncRT) doses is challenging, especially for Microbeam Radiotherapy (MRT), which is characterised by very high dynamic ranges with spatial resolutions on the micrometer scale. Monte Carlo (MC) simulation is considered a gold standard for accurate dose calculation in radiotherapy, and is therefore routinely relied upon to produce verification data. We present a MC model for Australian Synchrotron's Imaging and Medical Beamline (IMBL), which is capable of generating accurate dosimetry data to inform and/or verify SyncRT experiments. Our MC model showed excellent agreement with dosimetric measurement for Synchrotron Broadbeam Radiotherapy (S..

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Grants

Awarded by National Health and Medical Research Council of Australia


Funding Acknowledgements

Mr. Liam Day acknowledges PhD scholarship funding from RMIT University. Dr. Paolo Pellicioli acknowledges PhD scholarship funding from Grenoble Alpes University (UGA), and Swansea University. Dr. Paolo Pellicioli further thanks the European Synchrotron Radiation Facility (ESRF), Australian Nuclear Science and Technology Organisation (ANSTO)/Australian Synchrotron, and the Initiative d'excellence (IDEX) project of the UGA for funding and support. Dr. Lloyd Smyth acknowledges PhD scholarship funding from the University of Melbourne. This research is supported by the National Health and Medical Research Council of Australia's Project Grant Scheme (APP1061772). We thank ANSTO/Australian Synchrotron for the beamtime granted towards this project.