Bone microarchitecture in patients undergoing parathyroidectomy for management of secondary hyperparathyroidism
Irene Ruderman, Chamith S Rajapakse, Angelica Opperman, Patricia L Robertson, Rosemary Masterson, Mark K Tiong, Nigel D Toussaint
BONE REPORTS | ELSEVIER | Published : 2020
Background: Secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) leads to complex bone disease, affecting both trabecular and cortical bone, and increased fracture risk. Optimal assessment of bone in patients with CKD is yet to be determined. High-resolution magnetic resonance imaging (MRI) can provide three-dimensional assessment of bone microarchitecture, as well as determination of mechanical strength with finite element analysis (FEA). Methods: We conducted a single-centre, cross-sectional study to determine bone microarchitecture with MRI in CKD patients with SHPT undergoing parathyroidectomy. Within two weeks of surgery, MRI was performed at the distal tib..View full abstract
This work was supported by a research grant from the Amgen Osteoporosis Australia - ANZBMS Clinical Grants Program.