Journal article

Innate and adaptive immune responses in respiratory virus infection: implications for the clinic

John Stambas, Chunni Lu, Ralph A Tripp

EXPERT REVIEW OF RESPIRATORY MEDICINE | TAYLOR & FRANCIS LTD | Published : 2020

Abstract

INTRODUCTION: The innate immune response is the first line of defense and consists of physical, chemical and cellular defenses. The adaptive immune response is the second line of defense and is pathogen-specific. Innate immunity occurs immediately while adaptive immunity develops upon pathogen exposure, and is long-lasting, highly specific, and sustained by memory T cells. Respiratory virus infection typically induces effective immunity but over-exuberant responses are associated with pathophysiology. Cytokines expressed in response to viral infection can enhance biological responses, activate, and trigger signaling pathways leading to adaptive immunity Vaccines induce immunity, specifically..

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University of Melbourne Researchers