Conjunctival scarring, corneal pannus and Herbert's pits in adolescent children in trachoma-endemic populations of the Solomon Islands and Vanuatu.
Robert Butcher, Junely Tagabasoe, Joseph Manemaka, Annie Bong, Mackline Garae, Lui Daniel, Chrissy Roberts, Becca L Handley, Victor H Hu, Emma M Harding-Esch, Ana Bakhtiari, Rebecca Willis, Andreas Müller, John Kaldor, Richard Le Mesurier, David Mabey, Anasaini Cama, Oliver Sokana, Fasihah Taleo, Hugh R Taylor Show all
Clin Infect Dis | Published : 2020
BACKGROUND: In the Solomon Islands and Vanuatu, the sign trachomatous inflammation-follicular (TF) is common, but ocular infection with Chlamydia trachomatis is not. It is therefore debatable whether azithromycin mass drug administration (MDA), the recommended antibiotic treatment strategy for trachoma's elimination as a public health problem, is necessary in this setting. We set out to estimate what proportion of adolescents were at risk of progression of trachomatous scarring. METHODS: A cross-sectional survey was undertaken of all children aged 10-14 years resident in communities identified as high-TF clusters during previous population-based mapping. Graders examined children for clinica..View full abstract