Journal article
Conjunctival Scarring, Corneal Pannus, and Herbert's Pits in Adolescent Children in Trachoma-endemic Populations of the Solomon Islands and Vanuatu
R Butcher, J Tagabasoe, J Manemaka, A Bong, M Garae, L Daniel, C Roberts, BL Handley, VH Hu, EM Harding-Esch, A Bakhtiari, R Willis, A Müller, J Kaldor, R Le Mesurier, D Mabey, A Cama, O Sokana, F Taleo, HR Taylor Show all
Clinical Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2021
DOI: 10.1093/cid/ciaa1151
Abstract
Background: In the Solomon Islands and Vanuatu, the sign trachomatous inflammation - follicular (TF) is common, but ocular infection with Chlamydia trachomatis is not. It is therefore debatable whether azithromycin mass drug administration (MDA), the recommended antibiotic treatment strategy for trachoma's elimination as a public health problem, is necessary in this setting. We set out to estimate what proportion of adolescents were at risk of progression of trachomatous scarring. Methods: A cross-sectional survey was undertaken of all children aged 10-14 years resident in communities identified as high-TF clusters during previous population-based mapping. Graders examined children for clini..
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Awarded by Fred Hollows Foundation
Funding Acknowledgements
Fieldwork was funded by The Fred Hollows Foundation. Laboratory work and the salaries of R. B. and B. L. H. were funded by the Fred Hollows Foundation, the Queen Elizabeth Diamond Jubilee Trust and the International Trachoma Initiative (ITI) through a collaborative award managed by The Fred Hollows Foundation [1954-0]. E. M. H-E. and A. Ba. are funded by the International Trachoma Initiative. ITI is a program of The Task Force for Global Health and receives funding from Pfizer Inc. Neither ITI nor Pfizer Inc. had any role in the study's design; in the collection, analysis, and interpretation of data; in the writing of the publication; or in the decision to submit for publication.