Journal article

The role and contribution of treatment and imaging modalities in global cervical cancer management: survival estimates from a simulation-based analysis

Zachary J Ward, Surbhi Grover, Andrew M Scott, Sungmin Woo, Dina H Salama, Elizabeth C Jones, Tarek El-Diasty, Bradley R Pieters, Edward L Trimble, H Alberto Vargas, Hedvig Hricak, Rifat Atun

The Lancet Oncology | ELSEVIER SCIENCE INC | Published : 2020

Abstract

BACKGROUND: Cervical cancer is the fourth most common cancer among women worldwide, causing more than 300 000 deaths globally each year. In addition to screening and prevention, effective cancer treatment is needed to reduce cervical cancer mortality. We discuss the role of imaging in cervical cancer management and estimate the potential survival effect of scaling up imaging in several different contexts. METHODS: Using a previously developed microsimulation model of global cancer survival, we estimated stage-specific cervical cancer 5-year net survival in 200 countries and territories. We evaluated the potential survival effect of scaling up treatment (chemotherapy, surgery, radiotherapy, a..

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Grants

Awarded by National Cancer Institute P30 Cancer Center Support Grant


Funding Acknowledgements

This study was funded by the Harvard T H Chan School of Public Health and the National Cancer Institute P30 Cancer Center Support Grant (P30 CA008748) to Memorial Sloan Kettering Cancer Center. ECJ and ELT are employed by the National Institutes of Health.