Journal article

Quantifying the Effect of Location Matching on Accuracy of Multiparametric Magnetic Resonance Imaging Prior to Prostate Biopsy-A Multicentre Study

Dominic James Gavin, Jonathan Kam, Matthew Krelle, Mark Louie-Johnsun, Tom Sutherland, Samantha Koschel, Mark Jenkins, Yuigi Yuminaga, Raymond Kim, Kushlan Aluwihare, Sarah Skinner, Janelle Brennan, Lih-Ming Wong

European Urology Open Science | ELSEVIER | Published : 2020


Background: Multiparametric magnetic resonance imaging (mpMRI) has shown promise to improve detection of prostate cancer over conventional methods. However, most studies do not describe whether the location of mpMRI lesions match that of cancer found at biopsy, which may lead to an overestimation of accuracy. Objective: To quantitate the effect of mapping locations of mpMRI lesions to locations of positive biopsy cores on the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of mpMRI. Design, setting, and participant: We retrospectively identified patients having mpMRI of the prostate preceding prostate biopsy at three centres from 2013 to 2016. M..

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