Journal article

Effect of exercise on pain processing and motor output in people with knee osteoarthritis: a systematic review and meta-analysis

M Hall, F Dobson, M Plinsinga, C Mailloux, S Starkey, E Smits, P Hodges, B Vicenzino, SM Schabrun, H Masse-Alarie



OBJECTIVE: Guidelines recommend exercise as a core treatment for knee osteoarthritis. However, it is unclear how exercise affects measures of pain processing and motor function. The aim was to evaluate the effect of exercise on measures of pain processing and motor function in people with knee osteoarthritis. METHODS: We searched five electronic databases (MEDLINE, EMBASE, CINAHL, SCOPUS and Cochrane Central Register of Controlled Trials) for studies on knee osteoarthritis, of any design, evaluating pain processing and motor function before and after exercise. Data were pooled with random-effects meta-analysis. Study quality was assessed using the Downs and Black and quality of evidence was ..

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Awarded by NHMRC

Awarded by CIHR fellowship

Awarded by NHMRC Centre of Research Excellence grant

Funding Acknowledgements

MH is supported by a Sir Randal Heymanson Research Fellowship from The University of Melbourne. PH is supported by an NHMRC Senior Principal Research Fellowship (APP1102905). SMS is support by a NHMRC Career Development Fellowship (APP1104050). HMA was supported by a CIHR fellowship (358797). The project was supported by funds from an NHMRC Program Grant (APP1091302) and NHMRC Centre of Research Excellence grant (APP1079078). Funding sources had no role in study design, data collection, data analysis, data interpretation, or writing the manuscript.