Trajectories of asthma and allergies from 7 to 53 years and their relationship with middle-aged lung function and extra-pulmonary comorbidity profiles: a prospective cohort study

Dinh Bui; Caroline Lodge; Jennifer Perret; Adrian Lowe; Garun HAMILTON; Bruce Thompson; Graham Giles; Bircan Erbas; Jane Pirkis; Flavia Cicutini; Raisa Cassim; Gayan Bowatte; Paul Thomas; John Hopper; Michael Abramson; Haydn Walters; Shyamali Dharmage

Journal article

Trajectories of asthma and allergies from 7 to 53 years and their relationship with middle-aged lung function and extra-pulmonary comorbidity profiles: a prospective cohort study

Dinh Bui, Caroline Lodge, Jennifer Perret, Adrian Lowe, Garun HAMILTON, Bruce Thompson, Graham Giles, Bircan Erbas, Jane Pirkis, Flavia Cicutini, Raisa Cassim, Gayan Bowatte, Paul Thomas, John Hopper, Michael Abramson, Haydn Walters, Shyamali Dharmage

The Lancet Respiratory Medicine | Elsevier | Published : 2021

DOI: 10.1016/S2213-2600(20)30413-6

Abstract

Background Longitudinal trajectories of asthma and allergies from childhood to adulthood might be differentially associated with lung function and chronic obstructive pulmonary disease (COPD), but associations with extrapulmonary comorbidities have not been well investigated. We aimed to assess these trajectories and examine their associations with lung function outcomes and profiles of comorbidities. Methods In this prospective cohort study, data for asthma and related allergic conditions (ie, eczema, hay fever, and food allergy) were prospectively collected from the Tasmanian Longitudinal Health Study for participants aged 7–53 years originally recruited in Tasmania, Australia. All survivi..

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University of Melbourne Researchers

Dinh Bui Author

Caroline Lodge Author

Jennifer Perret Author

Adrian Lowe Author

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Grants

Funding Acknowledgements

National Health and Medical Research Council of Australia, EU's Horizon 2020, The University of Melbourne, Clifford Craig Medical Research Trust of Tasmania, The Victorian, Queensland & Tasmanian Asthma Foundations, The Royal Hobart Hospital, Helen MacPherson Smith Trust, and GlaxoSmithKline.