Is short-term exposure to grass pollen adversely associated with lung function and airway inflammation in the community?
Nur Sabrina Idrose, Rachel CA Tham, Caroline J Lodge, Adrian J Lowe, Dinh Bui, Jennifer L Perret, Don Vicendese, Edward J Newbigin, Mimi LK Tang, Fahad M Aldakheel, Nilakshi T Waidyatillake, Jo A Douglass, Michael J Abramson, Eugene Haydn Walters, Bircan Erbas, Shyamali C Dharmage
Allergy | WILEY | Published : 2020
BACKGROUND: The association between grass pollen exposure and early markers of asthma exacerbations such as lung function changes and increase in airway inflammation is limited. We investigated the associations between short-term grass pollen exposure and lung function and airway inflammation in a community-based sample, and whether any such associations were modified by current asthma, current hay fever, pollen sensitization, age and other environmental factors. METHODS: Cross-sectional and short-term analyses of data from the Melbourne Atopy Cohort Study (MACS) participants (n=936). Lung function was assessed using spirometry. Airway inflammation was assessed by fractional exhaled nitric o..View full abstract
Australian National Health and Medical Research Council (NHMRC).