Journal article

Differing mechanisms of atrial fibrillation in athletes and non-athletes: alterations in atrial structure and function

Siddharth J Trivedi, Guido Claessen, Luke Stefani, M Darragh Flannery, Paula Brown, Kristel Janssens, Adrian Elliott, Prashanthan Sanders, Jonathan Kalman, Hein Heidbuchel, Liza Thomas, Andre La Gerche

European Heart Journal - Cardiovascular Imaging | OXFORD UNIV PRESS | Published : 2020

Abstract

AIMS: Atrial fibrillation (AF) is more common in athletes and may be associated with adverse left atrial (LA) remodelling. We compared LA structure and function in athletes and non-athletes with and without AF. METHODS AND RESULTS: Individuals (144) were recruited from four groups (each n = 36): (i) endurance athletes with paroxysmal AF, (ii) endurance athletes without AF, (iii) non-athletes with paroxysmal AF, and (iv) non-athletic healthy controls. Detailed echocardiograms were performed. Athletes had 35% larger LA volumes and 51% larger left ventricular (LV) volumes vs. non-athletes. Non-athletes with AF had increased LA size compared with controls. LA/LV volume ratios were similar in bot..

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Grants

Awarded by National Health and Medical Research Council of Australia


Awarded by Cardiac Society of Australia and New Zealand Research Scholarship


Awarded by National Health and Medical Research Council Postgraduate Scholarship


Awarded by National Heart Foundation Future Leader Fellowship


Funding Acknowledgements

The study was funded, in part, by a Project Grant from the National Health and Medical Research Council of Australia (APP1130353): Atrial remodelling and risk of arrhythmias in endurance athletes. S.J.T. is supported by the Cardiac Society of Australia and New Zealand Research Scholarship (R52/18) and the National Health and Medical Research Council Postgraduate Scholarship (1168854). G.C. is supported by the Frans Van De Werf Fund for Clinical Cardiovascular Research and the Mathilde Horlait-Dapsens Scholarship. A.L.G. is supported by a National Heart Foundation Future Leader Fellowship (102206).