EcoToxChip: A next-generation toxicogenomics tool for chemical prioritization and environmental management
Niladri Basu, Doug Crump, Jessica Head, Gordon Hickey, Natacha Hogan, Steve Maguire, Jianguo Xia, Markus Hecker
Environmental Toxicology and Chemistry | Wiley | Published : 2019
Chemical contamination of natural ecosystems is regarded as one of our planet's greatest threats (Landrigan et al. 2018). Contaminant‐related phenomena such as malformed frogs, fish with tumors, and dwindling bird populations increasingly fuel societal concerns. Legislation in North America and Europe mandates the assessment and reduction of risk for thousands of commercially important chemical substances used by society and released into the environment. For example, large‐scale efforts such as the Chemicals Management Plan in Canada, the European Union's Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) program, and the US Environmental Protection Agency's (USEPA..View full abstract
We acknowledge the support of all team members, especially key projectmanagers (P. Poulin, A. Masse, J. Eng, E. Boulanger, L. Bidinosti, and A. Farhat) and our various trainees. We thank the financial sponsors of this project (Genome Canada; Genome Quebec; Genome Prairie; the Government of Canada; Environment and Climate Change Canada; Ministere-del' Economie, de la Science et de l'Innovation du Quebec the University of Saskatchewan; and McGill University) as well as core project partners (US Environmental Protection Agency, US Army Corps of Engineers, Qiagen, SGS AXYS, and Shell USA). We are grateful for the guidance offered by our program officer (M. Ayoub, Genome Quebec) and members of our Research Oversight Committee (chair: N. Denslow; members: K. Crofton, D. Schlenk, R. Suddaby, and C. Yauk).