Journal article

Risk of traumatic intracranial haemorrhage in children with bleeding disorders

Silvia Bressan, Paul Monagle, Stuart R Dalziel, Meredith L Borland, Natalie Phillips, Amit Kochar, Mark D Lyttle, John A Cheek, Jocelyn Neutze, Ed Oakley, Sarah Dalton, Yuri Gilhotra, Stephen Hearps, Jeremy Furyk, Franz E Babl

Journal of Paediatrics and Child Health | WILEY | Published : 2020

Abstract

AIM: To assess computerised tomography (CT) use and the risk of intracranial haemorrhage (ICH) in children with bleeding disorders following a head trauma. METHODS: Design: Multicentre prospective observational study. SETTING: 10 paediatric emergency departments (ED) in Australia and New Zealand. PATIENTS: Children <18 years with and without bleeding disorders assessed in ED following head trauma between April 2011 and November 2014. INTERVENTIONS: Data collection of patient characteristics, management and outcomes. MAIN OUTCOME MEASURES: Rate of CT use and frequency of ICH on CT. RESULTS: Of 20 137 patients overall, 103 (0.5%) had a congenital or acquired bleeding disorder. CT use was highe..

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Grants

Awarded by National Health and Medical Research Council, Canberra, Australia


Awarded by National Health and Medical Research Council (Centre of Research Excellence for Paediatric Emergency Medicine), Canberra, Australia


Awarded by Emergency Medicine Foundation, Brisbane, Australia


Awarded by Perpetual Philanthropic Services, Australia


Awarded by Auckland Medical Research Foundation


Awarded by Health Research Council of New Zealand


Funding Acknowledgements

We thank participating families, clinicians and research staff from the study sites. The study was funded by grants from the National Health and Medical Research Council (project grant GNT1046727, Centre of Research Excellence for Paediatric Emergency Medicine GNT1058560), Canberra, Australia; the Murdoch Children's Research Institute, Melbourne, Australia; the Emergency Medicine Foundation (EMPJ-11162), Brisbane, Australia; Perpetual Philanthropic Services (2012/1140), Australia; Auckland Medical Research Foundation (No. 3112011) and the A+Trust (Auckland District Health Board), Auckland, New Zealand; WA Health Targeted Research Funds 2013, Perth, Australia; the Townsville Hospital and Health Service Private Practice Research and Education Trust Fund, Townsville, Australia; and supported by the Victorian Government's Infrastructure Support Program, Melbourne, Australia. FEB's time was part funded by a grant from the Royal Children's Hospital Foundation and the Melbourne Campus Clinician Scientist Fellowship, Melbourne, Australia and an NHMRC Practitioner Fellowship, Canberra, Australia. SRD's time was part funded by the Health Research Council of New Zealand (HRC13/556).