Journal article

Toward a theory-based specification of non-pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations

Sietske Sikkes, Yi Tang, Roos J Jutten, Linda Wesselman, Lyn Turkstra, Alex Bahar-Fuchs, Jeanette Tamplin, Zara Thompson, Amit Lampit

Alzheimer's & Dementia | Elsevier | Published : 2021

Abstract

INTRODUCTION: Non-pharmacological treatments (NPTs) have the potential to improve meaningful outcomes for older people at risk of, or living with dementia, but research often lacks methodological rigor and continues to produce mixed results. METHODS: In the current position paper, experts in NPT research have specified treatment targets, aims and ingredients using an umbrella framework, the Rehabilitation Treatment Specification System. RESULTS: Experts provided a snapshot and an authoritative summary of the evidence for different NPTs based on the best synthesis efforts, identified main gaps in knowledge and relevant barriers, and provided directions for future research. Experts in trial me..

View full abstract

Grants

Awarded by ABFNHMRC Fellowship


Awarded by SAMS JPND


Awarded by Alzheimer Nederland


Awarded by Zon-MW Memorabel


Awarded by RJZon-MW Memorabel


Awarded by LWJPNDZon


Awarded by Synaptikon GmbH in the field of cognitive assessment and training


Awarded by KLNHMRC-ARC Dementia Research Development Fellowship


Funding Acknowledgements

ABFNHMRC Fellowship GNT1135605, SAMS JPND Zon-MW733051043, Alzheimer Nederland WE.26-2018-03, Zon-MW Memorabel 733050205, RJZon-MW Memorabel 733050205, LWJPNDZon-MW733051043, GCEuropean Union Horizon 2020 program, Inserm, Fondation d'entreprise MMA des Entrepreneurs du Futur, Fondation Alzheimer, Programme Hospitalier de Recherche Clinique, Region Normandie, Association France Alzheimer etmaladies apparentees, Fondation Vaincre Alzheimer, RMD Association of Support VCVGZ for Chair Psychosocial care for people with dementia to stimulate further development, AL partially funded by a grant from theGerman Federal Ministry of Education and Research (BMBF) for industry collaboration with Synaptikon GmbHin the field of cognitive assessment and training (ID 13GW0212A, 2017-2019). Received grants from theUniversity of Melbourne and the Berlin University Alliance for development and piloting of systems for cognitive training personalization and delivery of simultaneous cognitive and physical exercise (2019-2021); KLNHMRC-ARC Dementia Research Development Fellowship GNT1097435.