Journal article
Physical Functioning, Mental Health, and Quality of Life in Different Congenital Heart Defects: Comparative Analysis in 3538 Patients From 15 Countries
P Moons, K Luyckx, C Thomet, W Budts, J Enomoto, MA Sluman, CW Lu, JL Jackson, P Khairy, SC Cook, S Chidambarathanu, L Alday, K Eriksen, M Dellborg, M Berghammer, B Johansson, AS Mackie, S Menahem, M Caruana, G Veldtman Show all
Canadian Journal of Cardiology | Published : 2021
Abstract
Background: We compared physical functioning, mental health, and quality of life (QoL) of patients with different subtypes of congenital heart disease (CHD) in a large international sample and investigated the role of functional class in explaining the variance in outcomes across heart defects. Methods: In the cross-sectional Assessment of Patterns of Patient-Reported Outcome in Adults with Congenital Heart Disease-International Study (APPROACH-IS), we enrolled 4028 adult patients with CHD from 15 countries. Diagnostic groups with at least 50 patients were included in these analyses, yielding a sample of 3538 patients (median age: 32 years; 52% women). Physical functioning, mental health, an..
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Awarded by Cardiac Children's Foundation Taiwan
Funding Acknowledgements
This work was supported by the Research Fund-KU Leuven, Leuven, Belgium, through grant OT/11/033 (to K.L. and P.M.); by the Swedish Heart-Lung Foundation, Sweden, through grant number 20130607 (to M.D.); by the University of Gothenburg Centre for Person-Centred Care, Gothenburg, Sweden (to M.D. and P.M.); and by the Cardiac Children's Foundation, Taiwan, through grant CCF201302 (to H.L.Y.). This work was endorsed by, and conducted in collaboration with, the International Society for Adult Congenital Heart Disease. Registration: ClinicalTrials.gov: NCT02150603.