Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders

Y Patel; N Parker; J Shin; D Howard; L French; SI Thomopoulos; E Pozzi; Y Abe; C Abé; A Anticevic; M Alda; A Aleman; C Alloza; S Alonso-Lana; SH Ameis; E Anagnostou; AA McIntosh; C Arango; PD Arnold; P Asherson; F Assogna; G Auzias; R Ayesa-Arriola; G Bakker; N Banaj; T Banaschewski; CE Bandeira; A Baranov; N Bargalló; CHD Bau; S Baumeister; BT Baune; MA Bellgrove; F Benedetti; A Bertolino; PSW Boedhoe; M Boks; I Bollettini; C Del Mar Bonnin; T Borgers; S Borgwardt; D Brandeis; BP Brennan; JM Bruggemann; R Bülow; GF Busatto; S Calderoni; VD Calhoun; R Calvo; EJ Canales-Rodríguez; DM Cannon; VJ Carr; N Cascella; M Cercignani; TM Chaim-Avancini; A Christakou; D Coghill; A Conzelmann; B Crespo-Facorro; AI Cubillo; KR Cullen; RB Cupertino; E Daly; U Dannlowski; CG Davey; D Denys; C Deruelle; A Di Giorgio; EW Dickie; D Dima; K Dohm; S Ehrlich; BA Ely; T Erwin-Grabner; T Ethofer; DA Fair; AJ Fallgatter; SV Faraone; M Fatjó-Vilas; JM Fedor; KD Fitzgerald; JM Ford; T Frodl; CHY Fu; JM Fullerton; MC Gabel; DC Glahn; G Roberts; T Gogberashvili; JM Goikolea; IH Gotlib; R Goya-Maldonado; HJ Grabe; MJ Green; EH Grevet; NA Groenewold; D Grotegerd; O Gruber; P Gruner; A Guerrero-Pedraza

Journal article

Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders

Y Patel, N Parker, J Shin, D Howard, L French, SI Thomopoulos, E Pozzi, Y Abe, C Abé, A Anticevic, M Alda, A Aleman, C Alloza, S Alonso-Lana, SH Ameis, E Anagnostou, AA McIntosh, C Arango, PD Arnold, P Asherson Show all

JAMA Psychiatry | AMER MEDICAL ASSOC | Published : 2021

DOI: 10.1001/jamapsychiatry.2020.2694

Abstract

Importance: Large-scale neuroimaging studies have revealed group differences in cortical thickness across many psychiatric disorders. The underlying neurobiology behind these differences is not well understood. Objective: To determine neurobiologic correlates of group differences in cortical thickness between cases and controls in 6 disorders: attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BD), major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and schizophrenia. Design, Setting, and Participants: Profiles of group differences in cortical thickness between cases and controls were generated using T1-weighted magnetic reson..

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