Journal article

Wireless 'under the skull' epidural EEG and behavior in piglets during nitrous oxide or carbon dioxide gas euthanasia

Jean-Loup Rault, Alan Lai, Lauren Hemsworth, Matthias Le Chevoir, Sebastien Bauquier, Richard S Gates, Donald C Lay

Physiology & Behavior | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2020


Consciousness is central to animal welfare concerns. Its assessment is most often conducted based on behavior, with a poor understanding of the correspondence between behavior and the neurobiological processes that underlie the subjective experience of consciousness. Recording of brain electrical activity using electrodes placed under the skull improves EEG recording by minimizing artifacts from muscular or cardiac activities, and it can now be combined with wireless recording in free-moving animals. This experiment investigated the correspondence between wireless 'under the skull' epidural EEG and the behavior of 18 five-week-old female piglets undergoing nitrous oxide (N2O) or carbon dioxi..

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Awarded by United States Agriculture and Food Research Initiative

Funding Acknowledgements

This work was partially supported by a grant from the United States Agriculture and Food Research Initiative (#ILLW-2014-03869).