Journal article

In vivo immune cell dynamics in the human cornea

Luisa H Colorado, Katie Edwards, Holly R Chinnery, Haydee E Bazan

Experimental Eye Research | ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD | Published : 2020

Abstract

In vivo confocal microscopy (IVCM) allows the evaluation of the living human cornea at the cellular level. The non-invasive nature of this technique longitudinal, repeated examinations of the same tissue over time. Image analysis of two-dimensional time-lapse sequences of presumed immune cells with and without visible dendrites at the corneal sub-basal nerve plexus in the eyes of healthy individuals was performed. We demonstrated evidence that cells without visible dendrites are highly dynamic and move rapidly in the axial directions. A number of dynamic cells were observed and measured from three eyes of different individuals. The total average displacement and trajectory speeds of three ce..

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