Journal article

Harmonization of Outcomes and Vision Endpoints in Vision Restoration Trials: Recommendations from the International HOVER Taskforce

Lauren N Ayton, Joseph F Rizzo, Ian L Bailey, August Colenbrander, Gislin Dagnelie, Duane R Geruschat, Philip C Hessburg, Chris D McCarthy, Matthew A Petoe, Gary S Rubin, Philip R Troyk

TRANSLATIONAL VISION SCIENCE & TECHNOLOGY | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2020

Abstract

Translational research in vision prosthetics, gene therapy, optogenetics, stem cell and other forms of transplantation, and sensory substitution is creating new therapeutic options for patients with neural forms of blindness. The technical challenges faced by each of these disciplines differ considerably, but they all face the same challenge of how to assess vision in patients with ultra-low vision (ULV), who will be the earliest subjects to receive new therapies. Historically, there were few tests to assess vision in ULV patients. In the 1990s, the field of visual prosthetics expanded rapidly, and this activity led to a heightened need to develop better tests to quantify end points for clin..

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