Journal article

Diagnosis, prevalence, and clinical impact of sarcopenia in COPD: a systematic review and meta-analysis

Walter Sepulveda-Loyola, Christian Osadnik, Steven Phu, Andrea A Morita, Gustavo Duque, Vanessa S Probst

Journal of Cachexia, Sarcopenia and Muscle | WILEY | Published : 2020


Sarcopenia prevalence and its clinical impact are reportedly variable in chronic obstructive pulmonary disease (COPD) due partly to definition criteria. This review aimed to identify the criteria used to diagnose sarcopenia and the prevalence and impact of sarcopenia on health outcomes in people with COPD. This review was registered in PROSPERO (CRD42018092576). Five electronic databases were searched to August 2018 to identify studies related to sarcopenia and COPD. Study quality was assessed using validated instruments matched to study designs. Sarcopenia prevalence was determined using authors' definitions. Comparisons were made between people who did and did not have sarcopenia for pulmo..

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University of Melbourne Researchers


Awarded by Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior -Brasil (CAPES)

Funding Acknowledgements

This study was financed in part by the Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior -Brasil (CAPES) -Finance Code 001. WASL is supported by CAPES Brasil. VSP is supported by the Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) -Brasil.