Journal article

Safety and Efficacy of Reperfusion Therapies for Acute Ischemic Stroke Patients with Active Malignancy

Fabrizio Sallustio, Alfredo Paolo Mascolo, Federico Marrama, Giacomo Koch, Fana Alemseged, Alessandro Davoli, Valerio Da Ros, Daniele Morosetti, Daniel Konda, Marina Diomedi

Journal of Stroke and Cerebrovascular Diseases | ELSEVIER | Published : 2019

Abstract

BACKGROUND AND PURPOSE: Epidemiological correlations between active malignancy (AM) and acute ischemic stroke (AIS) are well-established. However, the effect of reperfusion strategies, particularly mechanical thrombectomy (MT), has been barely investigated in patients with AIS and AM. We aim to evaluate safety and efficacy of reperfusion strategies in such patients. MATERIALS AND METHODS: We performed a case-control analysis comparing patients with AM and AIS (AM group) to a group of cancer-free patients with AIS (control group). All enrolled patients underwent reperfusion therapies (i.e. intravenous thrombolysis, MT, intravenous thrombolysis plus MT). Main outcomes were 3-month functional i..

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