Journal article

The Administration of 100% Oxygen and Respiratory Drive in Very Preterm Infants at Birth

Jeroen J van Vonderen, Nadia E Narayen, Frans J Walther, Melissa L Siew, Peter G Davis, Stuart B Hooper, Arjan B te Pas

PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2013

Abstract

AIM: To retrospectively investigate the changes of SpO2 and respiratory drive in preterm infants at birth after administration of 100% oxygen. METHODS: Respiratory parameters, FiO2 and oximetry of infants 95% occurred more often in PPV group (53% vs. 69%) and lasted longer (70(40-95) vs. 120(50-202) s). In CPAP group, minute volume increased from 134 (76-265) mL/kg/min 1 minute before to 240 (157-370) mL/kg/min (p<0.01) 1 minute after start FiO2 1.0 and remained stable at 2 minutes (252 (135-376) mL/kg/min; ns). The rate of rise to maximum tidal volume increased (from 13.8 (8.0-22.4) mL/kg/s to 18.2 (11.0-27.5) mL/kg/s; p<0.0001) to 18.8 (11.8-27.8) mL/kg/s; ns). In the PPV group respiratory..

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Grants

Awarded by Veni-grant, The Netherlands Organisation for Health Research and Development (ZonMw), part of the Innovational Research Incentives Scheme Veni-Vidi-Vici


Funding Acknowledgements

A.B. te Pas is the recipient of a Veni-grant, The Netherlands Organisation for Health Research and Development (ZonMw), part of the Innovational Research Incentives Scheme Veni-Vidi-Vici, project number 91612027. J.J. van Vonderen is the recipient of a Willem-Alexander Children's Foundation scholarship www.willem-alexanderkinderfonds.nl. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.