Journal article
Performance of cardiovascular risk prediction equations in Indigenous Australians
ELM Barr, F Barzi, A Rohit, J Cunningham, S Tatipata, R McDermott, WE Hoy, Z Wang, PJ Bradshaw, L Dimer, PL Thompson, J Brimblecombe, K O'Dea, C Connors, P Burgess, S Guthridge, A Brown, A Cass, JE Shaw, L Maple-Brown
Heart | BMJ PUBLISHING GROUP | Published : 2020
Abstract
Objective To assess the performance of cardiovascular disease (CVD) risk equations in Indigenous Australians. Methods We conducted an individual participant meta-analysis using longitudinal data of 3618 Indigenous Australians (55% women) aged 30-74 years without CVD from population-based cohorts of the Cardiovascular Risk in IndigenouS People(CRISP) consortium. Predicted risk was calculated using: 1991 and 2008 Framingham Heart Study (FHS), the Pooled Cohorts (PC), GloboRisk and the Central Australian Rural Practitioners Association (CARPA) modification of the FHS equation. Calibration, discrimination and diagnostic accuracy were evaluated. Risks were calculated with and without the use of c..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
The CRISP consortium has received funding from the National Heart Foundation of Australia (Vanguard grant #100595) and a National Health and Medical Research Council (NHMRC) programme grant (#631947). ELMB was supported by a National Heart Foundation postdoctoral fellowship (#101291). LM--B was supported by NHMRC Fellowship (#605837) and NHMRC Practitioner Fellowship (#1078477). JC was supported by an NHMRC Research Fellowship (#1058244). JS was supported by a NHMRC Senior Research Fellowship (#1079438).