Oxidative damage of proline residues by nitrate radicals (NO3): a kinetic and product study
Joses G Nathanael, Jonathan M White, Annika Richter, Madison R Nuske, Uta Wille
Organic & Biomolecular Chemistry | ROYAL SOC CHEMISTRY | Published : 2020
Kinetic studies in acetonitrile revealed that proline residues in peptides are considerably protected against radical-induced oxidative damage by the neighbouring peptide bonds, compared with the single amino acid.
This work was supported by the Australian Research Council through the Linkage, Infrastructure, Equipment and Facilities (LIEF) Grant Scheme and The University of Melbourne through the High-Performance Computing facility.<SUP>31</SUP>